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Starpharma Holdings Announces DEP irinotecan Boosts Immuno-Oncology in Colon Cancer Models

29 Jun 2020  |  09:22:00  |  Associate analysts  |  Increase  |  Decrease  |  

Original announcement: DEP irinotecan boosts immuno-oncology in colon cancer models

Starpharma Holdings announced its SN-38 nanoparticle, DEP irinotecan in combination with an immunooncology (IO) agent (anti PD-1 antibody) showed superior anti-tumour activity and survival benefit in two colorectal cancer (CRC) models when compared to the anti PD-1 antibody alone. These results included improvement in both survival and efficacy in the particularly aggressive CT-26 CRC mode. IO agents are important treatments in several major cancers and the market for these agents is expected to exceed US$55bn by 2025, and include Merck's Keytruda, BMS' Yervoy and AstraZeneca's Imfinzi.

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